Nature is the biggest designer and the main source of inspiration and it is the inspiration to provide balanced and sustainable design solutions, the systems in nature were not limited to biological science only, but it is the source of a large database of strategies and mechanisms that can be achieved in the designs of interior architecture. Nature has a large number of bacteria, plants, etc... These organisms provide sources of inspiration and can be studied and applied in different ways by simulating their shape, and characteristics. The biological simulation approach (biomimetic) can be developed and creative by it using modern technology. Contemporary designs have emerged that merge within its various sciences such as advanced biological sciences, environmental sciences, and digital technology. In this merging, a product has been presented that exceeds science and creativity and that product cannot be reached without mixing traditional design thoughts and technological development.