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EFFECT OF RAW GARLIC CONSUMPTION ON THE LIPID PARAMETERS OF PATIENTS WITH DYSLIPIDEMIA

Article

Last updated: 23 Dec 2024

Subjects

-

Tags

Medicine

Abstract

Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD). It is manifested by solitary or combined disturbed levels of plasma lipids such as increased levels of total cholesterol (TC), increased levels of low-density lipoprotein cholesterol (LDL-C), elevated levels of triglycerides (TG), and a low level of high-density lipoprotein cholesterol (HDL-C). Dyslipidemia management includes lifestyle modifications and lipid-lowering medications. It has been reported that many patients are nonadherent adequately to medications. Garlic (Allium Sativum) is a common ingredient in food recipes. Owing to the content of bioactive compounds, garlic has been studied for its medicinal and therapeutic effects in the management of multiple diseases.  The study aimed to determine the possible effect of daily dietary intake of raw garlic on the lipid profile of dyslipidemia patients. The study included 50 adult participants with newly discovered dyslipidemia, without an obvious cardiovascular complication. They were instructed to consume 5 gm fresh raw garlic daily for 4 weeks. A Lipid profile was done at the beginning and end of the study. The results revealed that anthropometric measures showed non-significant statistical differences. The lipid profile revealed a highly significant statistical difference regarding TC, HDL-C, TG, VLDL, and non-HDL-C, while LDL-C was of non-significant statistical difference. Atherogenic ratios (TC/HDL-C, LDL-C/HDL-C, and TG/HDL-C) showed a highly significant statistical difference. Daily consumption of  5 gm of raw garlic improved some lipid profile parameters. Thus, it would help as an adjuvant intervention for patients with dyslipidemia.
 

DOI

10.21608/jes.2024.317417.1862

Keywords

Garlic, Allium sativum, dyslipidemia, Lipid profile

Authors

First Name

Ghada

Last Name

Ibraheem

MiddleName

S.

Affiliation

Faculty of Graduate Studies and Environmental Research, Ain Shams University, Cairo

Email

ghada.saber.ibraheem.std@iesr.asu.edu.eg

City

Cairo

Orcid

-

First Name

Moustafa

Last Name

Ragab

MiddleName

H.

Affiliation

Faculty of Graduate Studies and Environmental Research, Ain Shams University

Email

moustafa.ragab@iesr.asu.edu.eg

City

Cairo

Orcid

-

First Name

Sara

Last Name

Mahmoud

MiddleName

M.

Affiliation

Faculty of Graduate Studies and Environmental Research, Ain Shams University

Email

sara.attaya@iesr.asu.edu.eg

City

Cairo

Orcid

0000-0001-7877-1487

Volume

53

Article Issue

11

Related Issue

51556

Issue Date

2024-11-01

Receive Date

2024-09-02

Publish Date

2024-11-01

Page Start

3,007

Page End

3,021

Print ISSN

1110-0826

Online ISSN

2636-3178

Link

https://jes.journals.ekb.eg/article_391569.html

Detail API

https://jes.journals.ekb.eg/service?article_code=391569

Order

391,569

Type

Original Article

Type Code

500

Publication Type

Journal

Publication Title

Journal of Environmental Science

Publication Link

https://jes.journals.ekb.eg/

MainTitle

EFFECT OF RAW GARLIC CONSUMPTION ON THE LIPID PARAMETERS OF PATIENTS WITH DYSLIPIDEMIA

Details

Type

Article

Created At

23 Dec 2024