Eighty random samples of poultry thigh and breast (40 of each) as well as 100 random samples of poultry giblets (liver, kidney, heart spleen and gizzard, 20 of each) were collected from different retail shops in El Gharbia Governorate. The collected thigh and breast samples were subjected to bacteriological examination as well as determination of pH and antibiotic residues, while the giblets were examined only for detection of antibiotic residues. The bacteriological examination revealed that the mean value of aerobic plate count of the examined chicken thigh was 1.4 *100 4 x 10' and 6 x 10 = 2 × 104 for the examined chicken breast. While the mean values of total Staphylococcus count of the examined chicken thigh and breast samples were 8.9 x 10° 0.3 x 109 and 2.7 x 10° 1.7 x 104, respectively. The incidence of coagulase positive staphylococci in the examined chicken thigh and breast samples was 38.7 % and 51.5%, respectively. Salmonellae were isolated from both thigh and breast (2% each). E. coli was isolated from 32.5 % and 10% of the examined chicken thigh and breast samples, respectively. Isolated E. coli was serotyped into Oss : K59 (B3), 086 : K61 (B7), 0119 K89 (B19), 0124 : K72 (B17) and O126 : K71, (B16) serovars from 13 samples of thigh muscles while four samples of 086: K61 (B7), and breast samples belonged to serovars 0119 : K69 (B19), 0124 : K72 (B17). Determination of pH values declered that the mean values of the examined chicken thigh and breast samples were 6.4 +0.05 and 5.9 +0.03, respectively. Regarding antibiotic residues, 42.5% and 12.5% of the examined chicken thigh and breast samples contained antibiotic residues, respectively. Higher incidence of antibiotic residues was detected in poultry giblets as liver (85%), kidney (80%) heart (60%) spleen (75%) and gizzard (45%) which was considered of a great health hazard problems.