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31105

Synergistic antimicrobial combination with cumin extract and some antibiotics on Staphylococcus aureus from chickens

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Last updated: 04 Jan 2025

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Abstract

In the present study, antimicrobial activity of methanol Cuminum cyminum extract (50mg/ml) in combination with some
antibiotics were investigated against Staphylococcus aureus isolates. The antimicrobial sensitivity pattern of these
isolates in vitro was done and the intermediate isolates were checked for combination with methanol Cuminum cyminum
extract after detecting their antimicrobial activities against these isolates by both disc diffusion test and MIC and the
results showed that the antimicrobial activities of rifampicin, enrofloxacin, doxycycline, gentamicin, and erythromycin
were enhanced in combination with methanol Cuminum cyminum extract the obtained data showed that enhancement by
both disc diffusion test and MIC for methanol Cuminum cyminum extract and each of mentioned antibiotics in decimal
assay of additivity ratio (0.5 for rifampicin and erythromycin and 0.5 for extract ,0.7 for enrofloxacin, and 0.3 for
extract,0.6 for doxycycline, gentamicin and 0.4 for extract) against S.aureus isolates

DOI

10.21608/bvmj.2017.31105

Keywords

Antimicrobial combination, Staphylococcus aureus, cumin extract, antibiotics, Synergism

Authors

First Name

Ashraf

Last Name

Abd EL-Tawab

MiddleName

A.

Affiliation

Department of Bacteriology, Immunology and Mycology Fac. Vet. Med Benha University, Egypt

Email

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City

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Orcid

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First Name

Ahmed

Last Name

Ammar

MiddleName

M. A.

Affiliation

Department of Microbiology Fac. Vet. Med Zagazig University, Egypt

Email

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City

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Orcid

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First Name

Ahmed

Last Name

Hamouda

MiddleName

M. A.

Affiliation

Department of Microbiology Animal Health Research institute Egypt

Email

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City

-

Orcid

-

First Name

Fatma

Last Name

El-Hofy

MiddleName

I. A.

Affiliation

Department of Bacteriology, Immunology and Mycology Fac. Vet. Med Benha University, Egypt

Email

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City

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Orcid

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First Name

Abdelrahman

Last Name

Elgamal

MiddleName

A. A.

Affiliation

Department of Bacteriology, Immunology and Mycology Fac. Vet. Med Benha University, Egypt

Email

-

City

-

Orcid

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Volume

32

Article Issue

1

Related Issue

5334

Issue Date

2017-03-01

Receive Date

2019-05-05

Publish Date

2017-03-01

Page Start

7

Page End

12

Print ISSN

1110-6581

Online ISSN

2974-4806

Link

https://bvmj.journals.ekb.eg/article_31105.html

Detail API

https://bvmj.journals.ekb.eg/service?article_code=31105

Order

2

Type

Original Article

Type Code

812

Publication Type

Journal

Publication Title

Benha Veterinary Medical Journal

Publication Link

https://bvmj.journals.ekb.eg/

MainTitle

Synergistic antimicrobial combination with cumin extract and some antibiotics on Staphylococcus aureus from chickens

Details

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Article

Created At

22 Jan 2023