This paper reports an effective approach for synthesis of MOF-199 through solvothermal method. The synthesized MOF-199 was characterized by sets of different techniques such as FT-IR, and SEM and applied successfully for adsorption of methylene blue dye from simulated aqueous solution. The FT-IR results indicated that MOF-199 was indeed synthesized and SEM confirmed that a crystalline framework was completely achieved and matched the fully octahedral shape. To understand adsorption fairly, the effects of initial dye concentration, pH of solution, adsorbent dosage, contact time and temperature on the adsorption process were studied. Kinetic studies, in addition, the two familiar isotherms; Langmuir and Freundlich models were also reported to determine the adsorption characteristics. The results of Adsorption experiments displayed that the adsorption kinetic and isotherms fitted well with pseudo 2^nd order and Langmuir model, respectively. The maximum uptake capacity of MB at 25^oC was found to be 103.5 mg.g^-1 and even after the 5^th run durability, the uptake capacity reduced only within 5%, proving that the framework of MOF-199 has good stability