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Bile Tract Emergencies: An Updated Data for Emergency Healthcare Professionals, Nursing, and Clinical Pathologists

Article

Last updated: 08 Feb 2025

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Subjects

-

Tags

Biochemistry

Abstract

Background: Gallbladder disease, including acute cholecystitis (AC) and biliary colic, is a common condition that primarily affects women, especially during pregnancy. It is influenced by various factors, including hormonal changes, multiparity, and obesity, which contribute to gallstone formation and complications. The prevalence of gallstones varies across regions and populations, with higher rates observed among certain ethnic groups and during pregnancy.

Aim: The aim of this study is to provide an updated overview of gallbladder-related emergencies, including the epidemiology, risk factors, pathophysiology, and clinical management, particularly focusing on emergency healthcare professionals, nurses, and clinical pathologists.

Methods: A review of current literature and clinical data was conducted to analyze the incidence, risk factors, pathogenesis, and clinical presentation of gallbladder disease, with a particular emphasis on pregnant women. The role of hormones such as estrogen and progesterone in gallstone formation and the effects of insulin resistance were also explored.

Results: Gallstones are more common in women, particularly during pregnancy, with incidence rates increasing with multiparity and obesity. Hormonal changes, especially elevated estrogen levels, contribute to gallstone formation, while insulin resistance further exacerbates the risk. The study also found that gallbladder disease in pregnancy may remain asymptomatic but can progress to acute cholecystitis, pancreatitis, or cholangitis, often requiring surgical intervention.

Conclusion: Gallbladder disease remains a significant health issue, particularly in pregnant women, and requires prompt diagnosis and management. Emergency healthcare professionals, including nurses and clinical pathologists, should be aware of the risk factors and clinical manifestations to provide effective care and reduce complications. Preventive measures, including lifestyle changes and careful monitoring in high-risk populations, are essential for managing this condition

DOI

10.21608/ejchem.2025.344788.10993

Keywords

gallstones, Acute Cholecystitis, Biliary Colic, Pregnancy, Hormonal changes

Authors

First Name

Nasser Owaid

Last Name

Alanazi

MiddleName

-

Affiliation

Armed Forces Hospital in Al Kharj, Ministry of Defense, Saudi Arabia

Email

alanizy420@gmail.com

City

-

Orcid

-

First Name

Fayez Suliman

Last Name

Alharbi

MiddleName

-

Affiliation

Qassim armed forces hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Mohammed Monawer H.

Last Name

Almotairi

MiddleName

-

Affiliation

Qassim armed forces hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Muneer Shudayyid Muneer

Last Name

Almutairi

MiddleName

-

Affiliation

Qassim armed forces hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Nawaf Hamad Nazal

Last Name

Alotaibi

MiddleName

-

Affiliation

Prince Sultan Air Base, Al-Kharj, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Othman Mohammed Z

Last Name

Alshehri

MiddleName

-

Affiliation

Armed Forces Medical Services, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Maryam Awwad

Last Name

Haldhafeerl

MiddleName

-

Affiliation

Northern Area Armed forces Hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Nada Ali

Last Name

Alkhaibari

MiddleName

-

Affiliation

Armed Forces Hospital in Al Kharj, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Khalaf Naif

Last Name

Alwahbi

MiddleName

-

Affiliation

Northern Area Armed forces Hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Naif Lafi Salem

Last Name

Alharbi

MiddleName

-

Affiliation

Northern Area Armed forces Hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Fahad Mohammed

Last Name

Almutairi

MiddleName

-

Affiliation

Northern Area Armed forces Hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Muteb Alhumaidy

Last Name

Alshammari

MiddleName

-

Affiliation

Northern Area Armed forces Hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Waleed Snaid

Last Name

Alharbi

MiddleName

-

Affiliation

Northern Area Armed forces Hospital, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Megdad Hassan Ali

Last Name

Nahari

MiddleName

-

Affiliation

Armed forces hospital southern region, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Ali Yahya

Last Name

Shrahili

MiddleName

-

Affiliation

Prince Sultan Military Medical City, Ministry of Defense, Saudi Arabia

Email

-

City

-

Orcid

-

Volume

68

Article Issue

2

Related Issue

53637

Issue Date

2025-02-01

Receive Date

2024-12-15

Publish Date

2025-02-01

Page Start

145

Page End

164

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 68_Issue 2_Pages 145-164.pdf

PDF . 354.0kB

Link

https://ejchem.journals.ekb.eg/article_406121.html

Detail API

http://journals.ekb.eg?_action=service&article_code=406121

Order

406,121

Type

Review Articles

Type Code

444

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Bile Tract Emergencies: An Updated Data for Emergency Healthcare Professionals, Nursing, and Clinical Pathologists

Details

Type

Article

Created At

08 Feb 2025