Good nutrition is essential for a balanced lifestyle and effectively addresses nutritional disturbances. Nutraceuticals, particularly flavonoids found in plant-derived foods, show diverse medical advantages, particularly anti-inflammatory and antimicrobial, and anti-cancer properties. Myricetin, a flavonol found in fruits and vegetables, is notable due the prospect of nutraceutical benefit and cancer-protective properties. Cancer is a major worldwide health problem, and existing treatments can lead to difficulties. Although breakthroughs in cancer therapy, it's still an important factor of mortality worldwide, with high expenditures and unpleasant consequences. Antioxidant-rich medicinal plants and biologically active compounds have the potential to avoid and treat diseases. To overcome these challenges, the search for alternative anticancer drugs is crucial. Herbal medicines, particularly flavonoids, significantly influence cellular and molecular mechanisms and channels associated with Cancer initiation and metastasis. Myricetin, a dietary flavanol, exhibits notable pharmacological activities, especially in the realm of anticancer effects against various human cancers. Myricetin, a polyhydroxy flavonol, emerges as a promising candidate, in cancer prevention is evident through various mechanisms, making it a subject of extensive research. This review provides a most recent record of research findings on myricetin's anticancer potential, emphasizing its multifaceted contributions, safety considerations, optimal doses for various types of cancer, and implications in experimental studies. Additionally, difficulties such as bioavailability improvement through nano-formulations and the synthesis of derivatives for further exploration are discussed. The evidence gathered underscores myricetin's potential as a synergistic agent with existing anticancer drugs and offers valuable insights for researchers in the field.