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406354

Intratonsillar Molecular Detection of some Herpesviruses with a Histopathological Study

Article

Last updated: 09 Apr 2025

OverviewSimilar Items

Subjects

-

Tags

Pathogenicity and virulence

Abstract

Background: Recurrent tonsillitis (CT) is a parenchymal infection of the palatine tonsils that is identified based on clinical criteria, some studies show a close relation between viral infections and tonsillitis. Objectives: The aim of our study is to determine the prevalence of some human herpesviruses (HHV) including HHV-4, HHV-6 and HHV-7 using the multiplex  polymerase chain reaction (mPCR) technique and to characterize the association between viruses and recurrent tonsillitis to evaluate the histopathological changes in tonsillar tissues among patients with tonsillitis Methodology: A total of (100) samples from patients of Basrah general hospital during period (Sep. 2023 to Feb. 2024) from both sexes were collected after surgical interventions from (54) males and (46) females with age ranged (2-50) years with regard to clinical information and molecular detection and histopathological study. Results: Our results showed that EBV (HHV-4 DNA) was detected in 20% samples, while positive results of HHV-6 DNA was 16%, tonsillitis  in  children  infected  with  HHV  type  6  is  characterized  by  a  longer course  of the disease, which leads to a longer hospital treatment and  the age group (6-10) years was more infected than other age groups, and the tonsillitis was predominantly in males more than women, while HHV-7 DNA was not amplified. Conclusion:  The current study concludes that the most common virus in the tonsils was EBV, then HHV6, with HHV7 not being diagnosed.

DOI

10.21608/ejmm.2025.349822.1426

Keywords

Tonsils, Tonsillectomy, EBV, HHV6, HHV7

Authors

First Name

Akeel

Last Name

Jassim

MiddleName

A.

Affiliation

Basrah Directorate of Education, Ministry of Education, Iraq

Email

mustafafadil837@gmail.com

City

Basra

Orcid

-

First Name

Hayder

Last Name

Al-Hmudi

MiddleName

A.

Affiliation

College of Science, University of Basrah, Basrah, Iraq

Email

-

City

-

Orcid

-

First Name

Maha

Last Name

Al-Mallak

MiddleName

K.

Affiliation

College of Science, University of Basrah, Basrah, Iraq

Email

-

City

-

Orcid

-

Volume

34

Article Issue

2

Related Issue

51523

Issue Date

2025-04-01

Receive Date

2025-01-02

Publish Date

2025-04-01

Page Start

233

Page End

241

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 34_Issue 2_Pages 233-241.pdf

PDF . 952.2kB

Link

https://ejmm.journals.ekb.eg/article_406354.html

Detail API

http://journals.ekb.eg?_action=service&article_code=406354

Order

28

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Intratonsillar Molecular Detection of some Herpesviruses with a Histopathological Study

Details

Type

Article

Created At

01 Feb 2025