The objective of this work was to assess the effects of replacing 10% of diet protein, equivalent to about 40% soybean protein with a bacteria-treated jojoba meal (JML) of a level of 10% with or without Alpinia galanga on reproductive performance of New-Zealand White rabbit (NZW) does. A total number of 42 NZW rabbit does aged 8 months. and weighed about 3.34 ± 0.079 kg were randomly allotted into three groups (14/each). The 1st group (CON) was provided with the basal diet. The 2nd group (JML) was provided with diets containing jojoba meal treated with (Lactobacillus acidophilus) at a level of 10% without Alpinia galanga and the 3rd group (JMLA) was provided with diets containing jojoba meal treated with (Lactobacillus acidophilus) at a level of 10 % plus 0.25% Alpinia galanga. Results showed that doe rabbits fed Alpinia galanga (JMLA) and bacteria-treated jojoba meal (JML) slightly improved body weight and fertility of does compared with those fed the control diet but results were not significant. Litter size at weaning did not increase significantly, but was the highest in JMLA and JML compared with CON group. Litter weight of doe rabbits from birth to weaning of JMLA and JML groups did not increase significantly, but was higher than the CON group. Results revealed that milk production was higher (P<.05) in JML and JMLA groups as compared with the CON group. Total feed intake in JML and JMLA treatment groups tended to be higher (P>.05) than that of the CON. Conculosively, the results of the current study underscore the importance of using biologically treated jojoba meal as a partial substitute of soybean meal protein in addition to the use of some medicinal plants such as Alpinia galanga to improve the reproductive performance of doe rabbits in North Sinai.