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392015

Evaluation of antibiotic potential of metabolic peptides derived from gut microbial samples using in Silico Approach

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Animal Physiology

Abstract

The antibiotic potential of metabolic peptides derived from Camel gut microbial sample is evaluated in this study using computational methods. Data on sequence of microbes isolated from the digestive system of Camel was retrieved from the sequence raw archive (Accession number SRR 13205865) of National Centre for Biotechnology Information. The retrieved sequence was subjected to genome assembly using the database of Bacterial Viral Bioinformatics Resource Centre. Identification of secondary metabolites was done using Anti SMASH server. The identified metabolic peptides include arylpolyene, phosphonate and NRPS. The antibiotic potential of the secondary metabolites was predicted using CAMPR3 server. The antibiotic potential of different regions of the metabolic peptides was predicted the antibacterial peptide prediction server. The result indicated positive antimicrobial potential of the secondary metabolites derived from microbes isolated from camel digestive system. Further research on the therapeutic potential of the identified metabolic peptides for the treatment of bacterial infections is recommended.

DOI

10.21608/ejsgs.2024.335711.1013

Keywords

antibiotic potential, camel gut microbial, biotechnology information, metabolic peptides

Authors

First Name

Ibrahim

Last Name

Musa

MiddleName

-

Affiliation

Department of Animal Science, Faculty of Agriculture, Nasarawa State University, Nigeria

Email

dribmazara@yahoo.com

City

Lafia

Orcid

-

Volume

19

Article Issue

3

Related Issue

51497

Issue Date

2024-12-01

Receive Date

2024-11-11

Publish Date

2024-12-01

Page Start

1

Page End

4

Print ISSN

2090-0386

Online ISSN

2090-0376

Link

https://ejsgs.journals.ekb.eg/article_392015.html

Detail API

https://ejsgs.journals.ekb.eg/service?article_code=392015

Order

1

Type

Original Article

Type Code

728

Publication Type

Journal

Publication Title

Egyptian Journal of Sheep and Goats Sciences

Publication Link

https://ejsgs.journals.ekb.eg/

MainTitle

Evaluation of antibiotic potential of metabolic peptides derived from gut microbial samples using in Silico Approach

Details

Type

Article

Created At

30 Dec 2024