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342946

Quinazolines Linked to Sugar Derivatives as Nucleoside Analogs, Synthesis and Biological Aspects

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Organic chemistry

Abstract

Quinazoline incorporating compounds have recently acquired intensive interest due to their several applications, the most important of which are those related to the divers bioactivities. Quinazoline derivatives have a variety of pharmacological effects providing a special interest to such heterocyclic systems as a basic core in bioactive structures. Techniques for synthesizing or modifying this ring structure are therefore always evolving and intriguing. As intermediates in the synthesis of various beneficial heterocyclic compounds, they are of considerable interest. Incorporation of sugar, in modified cyclic and acyclic forms, with the structure of heterocyclic possessing quinazoline system revealed potential structures with various bioactivities.

DOI

10.21608/ejchem.2024.259301.9116

Keywords

Quinazolinyl, Synthesis, Anticancer, Antimicrobial, Antiviral

Authors

First Name

Adel

Last Name

Abdel-Rahman

MiddleName

A.-H.

Affiliation

Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt

Email

adelnassar63@yahoo.com

City

-

Orcid

0000-0003-3319-8191

First Name

Eman M.

Last Name

El-Ganzoury

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt

Email

ganzoury90@gmail.com

City

Tala, menoufi

Orcid

-

First Name

Ibrahim F.

Last Name

Zeid

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt

Email

-

City

-

Orcid

-

First Name

Ehab M.

Last Name

Zayed

MiddleName

-

Affiliation

Green Chemistry Department, National Research Centre, 33 El-Bohouth St. (former El Tahrir St.), P.O. 12622, Dokki, Giza, Egypt

Email

ehab_zayed2002@yahoo.com

City

Giza

Orcid

0000-0003-1245-8732

First Name

Wael A.

Last Name

El-Sayed

MiddleName

-

Affiliation

Photochemistry Department, National Research Centre, Dokki, Giza, Egypt

Email

waelshendy@gmail.com

City

Giza, Egypt

Orcid

0000-0002-8232-1830

Volume

67

Article Issue

9

Related Issue

48208

Issue Date

2024-09-01

Receive Date

2023-12-30

Publish Date

2024-09-01

Page Start

209

Page End

223

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_342946.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=342946

Order

342,946

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Quinazolines Linked to Sugar Derivatives as Nucleoside Analogs, Synthesis and Biological Aspects

Details

Type

Article

Created At

30 Dec 2024