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350237

A Review of Iridoid Glycosides Content and Their Biological Properties from Genus Citharexylum

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

Citharexylum is a genus of flowering plants that belongs to Verbenaceae family. Various species of genus Citharexylum are cultivated as ornamentals. The species have various potent pharmacological and biological activities such as antioxidant, antidiabetic, antibacterial, anticancer and antipyretic effects. The Citharexylum botanical genus is a rich source of iridoid glycosides. All of the iridoids isolated from Citharexylum species have a- mono-glucosidic structure. The activity such as antinociceptive, antimicrobial, antischistosomal, cytotoxic, anticancer, hepatoprotective, nephroprotective, antispasmodic, muscle relaxation, antidiabetic, antiallergic, immunomodultory, antityrosinase and anticholinesterase was discussed. The study extended to the application of plant with high content of iridoid glycosides as well as the further search and future perspective. This review provides an exhaustive compilation of the iridoid glycosides-containing species of Citharexylum along with conjectures regarding potential biological activities, particularly those related to antioxidant and anti-inflammatory properties. The structure-activity relationships as anti-inflammatory and antioxidant agents have been illustrated.

DOI

10.21608/ejchem.2024.272834.9391

Keywords

Citharexylum, iridoid glycosides, biological activities, Anti-inflammatory, antioxidant, structure-activity relationship, future prospective

Authors

First Name

Howaida

Last Name

Abd-Alla

MiddleName

Ibrahim

Affiliation

Natural Compounds Chemistry Department, National Research Centre, Dokki, Giza, Egypt

Email

howaida_nrc@yahoo.com

City

Cairo

Orcid

0000-0001-9638-8481

First Name

Safaa

Last Name

Saad

MiddleName

A.

Affiliation

Natural Compounds Chemistry Department, NRC

Email

safaa_saad28@yahoo.com

City

Cairo

Orcid

-

First Name

Nagwa

Last Name

Shalaby

MiddleName

M.M.

Affiliation

Natural Compounds Chemistry Department, NRC

Email

nagwashalaby@hotmail.com

City

Cairo

Orcid

0000-0002-6800-5460

First Name

Hanan

Last Name

Aly

MiddleName

Farouk

Affiliation

Deprtment of Therapeutic Chemistry , National Research Centre (NRC),El Behouth St. , P.O.12622. Dokki, Giza, Egypt.

Email

hanan_abduallah@yahoo.com

City

Cairo

Orcid

0000-0003-3642-1571

First Name

Abd El-Moneim

Last Name

Afify

MiddleName

M.

Affiliation

1Biochemistry Department, Faculty of Agriculture, Cairo University, Egypt

Email

howaida.nrc@gmail.com

City

Cairo

Orcid

-

First Name

Hanaa

Last Name

Ali

MiddleName

F. M.

Affiliation

Biochemistry Department, Faculty of Agriculture, Cairo University, Egypt

Email

mohamed@agr.cu.edu.eg

City

Cairo

Orcid

-

First Name

Nadia

Last Name

Abdel-Moein

MiddleName

M.

Affiliation

Biochemistry Department, Faculty of Agriculture, Cairo University, Egypt

Email

dr_n_m2008@yahoo.com

City

Giza

Orcid

-

Volume

67

Article Issue

9

Related Issue

48208

Issue Date

2024-09-01

Receive Date

2024-02-27

Publish Date

2024-09-01

Page Start

45

Page End

63

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 67_Issue 9_Pages 45-63.pdf

PDF . 1.3MB

Link

https://ejchem.journals.ekb.eg/article_350237.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=350237

Order

350,237

Type

Review Articles

Type Code

444

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

A Review of Iridoid Glycosides Content and Their Biological Properties from Genus Citharexylum

Details

Type

Article

Created At

30 Dec 2024