Hyperlipidemia is characterized by the elevation of cholesterol, triglyceride, and LDL (low-density lipoprotein) blood concentrations. Hyperlipidemia is a risk factor for cardiovascular diseases, in addition to nonalcoholic fatty liver disease and hepatic cancer. Current treatment strategies for hyperlipidemia include lifestyle changes and lipid-lowering medications, which have serious side effects. Therefore, the aim of this review is describing what is known to date as lipid-lowering alternatives of natural source and therefore have fewer side effects. Many phenolic-rich plants were found to be effective in regulating lipid metabolism, as cassia bark, clove buds, coffee seeds, eucalyptus kino and leaves, ginger rhizomes, hops strobiles, juniper berry leaves, licorice roots, milk thistle seeds, peppermint leaves, pomegranate rind, and turmeric rhizomes.