Limited agricultural lands and water resources scarcity in Egypt lead to that the food supply would be insufficient to meet over-population needs so that we targeted to take part in solving the food gap problem through increasing wheat crop productivity by applying endophytic bacteria as biofertilizers. This study mainly aims to study the potentiality of endophytic bacteria isolated from avocado fruits (Persea americana) as biofertilizer in promoting of wheat plant (Triticum aestivum) growth via estimation of plant growth promoting criteria. From wheat seed experiment, out of 13 bacterial isolates from avocado fruits, five isolates increased germination percent as well as number and length of adventurous roots and shoot length. It was concluded that endophytic bacterial isolates from avocado fruits promote wheat seedling growth.