Organizations rely on employees to innovate in processes, methods and operations, because employees are the basic cells of the organization and play a fundamental role in organizational innovation. Since ideas are the foundation of innovation, these are generated by employees, who ''develop, carry, react to and modify ideas''. So the need to demonstrate innovative behaviors from employees, that it aids businesses in remaining competitive and adapt quickly to changes. However, to adopt the innovation process in any organization, inertia to change is a substantial barrier, and its role has not been examined completely. The purpose of this study is to examine the impact of organizational inertia on employee innovative behavior. A questionnaire was used to collect data from 353 teachers (with 90.93% response rate). Multiple Regression analysis was employed to test the research hypotheses using the software (SPSS V.25). The study findings showed that there is a significant negative impact of organizational inertia on employee innovative behavior. Also, theoretical and practical implications were presented in addition to future research suggestions.