This study aims to examine the effect of employees' perception of injustice on their intention to leave their jobs. It also explored the mediating role of job insecurity in the relationship between employees' perception of injustice and their intention to leave. The study analyzed 404 responses from five-star hotels and travel agencies in the Greater Cairo area of Egypt using the PLS-SEM approach. Results revealed that employees' perception of injustice positively impacts their intention to leave and job insecurity. In addition, job insecurity positively affects employees' intention to leave. Moreover, job insecurity mediates the relationship between employees' perception of injustice and their intention to leave. This study provides theoretical and practical insights into employee turnover, a significant issue in the Egyptian tourism and hospitality sector. The study highlights job insecurity as a key mediator in social exchange, influencing employees' intention to leave. It focuses on the hospitality and tourism industry, providing insights into the interactions between social exchange, perceived injustice, job insecurity, and turnover intention, enhancing the relevance of social exchange theory.