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380412

Probiotics as promoters of human health

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Last updated: 28 Dec 2024

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Abstract

Numerous common human disorders, including cancer, high blood pressure, high cholesterol, inflammatory bowel diseases, obesity, and oral health issues, have been linked to changes in the composition and activity of the gut microbiota. This review aimed to highlight the significance of probiotics due to their positive impacts on gut microbiota, overall human health, cancer prevention, and production of bioactive compounds. Therefore, modifying the gut microbiota's balance can be highly beneficial for maintaining the human health. Probiotics are live microbial supplements, when consumed with meals; they help the host by harmonizing his/ her intestinal microflora. Supplements containing these good bacteria can be used up, or they can be added to dairy-free or non-dairy foods and drinks. Probiotics are mainly categorized into two main genera; mainly Lactobacillus spp. and Bifidobacterium spp. Probiotics are vital for maintaining a healthy microbiota; especially in cancer patients. They enhance the production of anticancer enzymes, apoptosis, autophagy, immunology, and other processes. Additionally, probiotics produce various bioactive molecules such as short-chain fatty acids, enzymes, vitamins, and exopolysaccharides with antibacterial attributes. Consequently, probiotics are utilized in food technology to develop the functional foods that promote the human health.

DOI

10.21608/nrmj.2024.312723.1681

Keywords

functional food, microbiota, Bioactive substances, probiotics, Cancer

Authors

First Name

Mai

Last Name

N. Amer

MiddleName

-

Affiliation

Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), Giza, Egypt, 12622

Email

-

City

-

Orcid

0000-0002-9881-8382

First Name

Maissara

Last Name

M.K. Elmaghraby

MiddleName

-

Affiliation

Central Laboratory of Organic Agriculture, Agricultural Research Center (ARC), Giza, Egypt

Email

-

City

-

Orcid

0000-0001-7491-9421

First Name

Aya

Last Name

A.M. Abdellatif

MiddleName

-

Affiliation

Central Laboratory of Organic Agriculture, Agricultural Research Center (ARC), Giza, Egypt

Email

-

City

-

Orcid

0000-0002-8027-8373

First Name

Sondos

Last Name

R. Salem

MiddleName

-

Affiliation

Biotechnology Program, Faculty of Agriculture, Ain Shams University, Hadayek Shubra, Cairo 11241, Egypt

Email

-

City

-

Orcid

-

First Name

Mariam

Last Name

M. Salama

MiddleName

-

Affiliation

Biotechnology Program, Faculty of Agriculture, Ain Shams University, Hadayek Shubra, Cairo 11241, Egypt

Email

-

City

-

Orcid

-

First Name

Omar

Last Name

A. Abdel Maksoud

MiddleName

-

Affiliation

Biotechnology Program, Faculty of Agriculture, Ain Shams University, Hadayek Shubra, Cairo 11241, Egypt

Email

-

City

-

Orcid

-

First Name

Radwa

Last Name

M. Nasr

MiddleName

-

Affiliation

Biotechnology Program, Faculty of Agriculture, Ain Shams University, Hadayek Shubra, Cairo 11241, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

N.H. Amer

MiddleName

-

Affiliation

Therapeutic Nutrition Program, Faculty of Home Economics, Helwan University, Cairo 11241, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

M.H. Marghany

MiddleName

-

Affiliation

Plant and Microbiology Department, Faculty of Science, Cairo University, Giza, 12613, Egypt

Email

-

City

-

Orcid

-

First Name

Hassan

Last Name

M. Awad

MiddleName

-

Affiliation

Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), Giza, Egypt, 12622

Email

awadmhassan@yahoo.com

City

Cairo

Orcid

0000-0002-8744-5496

Volume

8

Article Issue

5

Related Issue

50276

Issue Date

2024-09-01

Receive Date

2024-08-15

Publish Date

2024-09-18

Page Start

2,580

Page End

2,603

Print ISSN

2537-0286

Online ISSN

2537-0294

Article File

NRMJ_Volume 8_Issue 5_Pages 2580-2603.pdf

PDF . 553.8kB

Link

https://nrmj.journals.ekb.eg/article_380412.html

Detail API

https://nrmj.journals.ekb.eg/service?article_code=380412

Order

380,412

Type

Review Article

Type Code

2,338

Publication Type

Journal

Publication Title

Novel Research in Microbiology Journal

Publication Link

https://nrmj.journals.ekb.eg/

MainTitle

Probiotics as promoters of human health

Details

Type

Article

Created At

28 Dec 2024