Beta
ManageSearchChatDiscover
286731

EVALUATING THE EFFECT OF A COMBINATION OF BLACKBERRY AND STRAWBERRY JUICES ON STZ-INDUCED OXIDATIVE STRESS OF DIABETIC RATS

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Biotechnology (Agricultural Chemistry, Agricultural Microbiology and Genetics)

Abstract

This investigation aims to examine the effect of a newly combination of blackberry and strawberry juice on diabetic rats. Fifty rats were used and divided into five groups, 10 rats for each group. The groups were divided as follows: The first groups a control group (NC), The second groups a group that took a combination of blackberry and strawberry juices (B+S) only, and a third group injected with streptozotocin (STZ): the fourth and fifth groups of diabetic rats were treated with a combination of juices (STZ+B+S) and metformin (STZ+Met), respectively. The experiment lasted 56 days; estimates were made on serum, liver homogenate, and histological examination of liver tissues at the end. The results showed that diabetic rats had significantly higher levels of glucose metabolism enzymes, tumor necrosis factor-alpha (TNF-α), interleukin 6 (IL-6), and significantly lower levels of hepatic antioxidants. Compared to the STZ group, diabetic rats given a combination of juices showed significant improvements in glucose metabolism enzymes, IL-6, and TNF-α levels, as well as significant increases in antioxidant enzyme activity. The results indicate that a combination of blackberry and strawberry juices can be a functional food that helps reduce diabetes complications.

DOI

10.21608/mjard.2022.286731

Keywords

blackberry, strawberry, streptozotocin, IL-6, and TNF-α

Volume

42

Article Issue

3

Related Issue

36806

Issue Date

2022-12-01

Receive Date

2023-02-21

Publish Date

2022-12-01

Page Start

411

Page End

430

Print ISSN

1110-0257

Online ISSN

2812-6505

Article File

MJARD_Volume 42_Issue 3_Pages 411-430.pdf

PDF . 1.3MB

Link

https://mjard.journals.ekb.eg/article_286731.html

Detail API

https://mjard.journals.ekb.eg/service?article_code=286731

Order

286,731

Type

Original Articles

Type Code

2,161

Publication Type

Journal

Publication Title

Minia Journal of Agricultural Research and Development

Publication Link

https://mjard.journals.ekb.eg/

MainTitle

EVALUATING THE EFFECT OF A COMBINATION OF BLACKBERRY AND STRAWBERRY JUICES ON STZ-INDUCED OXIDATIVE STRESS OF DIABETIC RATS

Details

Type

Article

Created At

28 Dec 2024