This investigation was conducted during two experimental seasons of 2020/2021 and 2021/2022 to explore the impact of fertilization (farmyard manure at rats 0, 10, 15 and 20 m³/fed., plus half-recommended dose of NPK fertilizer) and bio-fertilizers (seed inoculation with a mixture of bacteria; Azospirillum chroococcum, Bacillus megatherium var. phosphaticum, Bacillus circulans and/or arbuscular mycorrhizal fungi), as well as their interactions on growth, yield, and coriander volatile oil. Results showed a significant increase in plant growth traits, i.e., plant height, branches number, fresh and dry weight of plant, yield components, i.e., number of umbels per plant, seed yield per plant and per feddan, as well as volatile oil production. Treating plants with a high rate of farmyard manure registered the highest values of parameters under study. Also, adding a mixture of bacteria; A. chroococcum, B. megatherium var. phosphaticum, B. circulans with arbuscular mycorrhizal fungi proved to be more effective in increasing the previously studied traits. The tested characteristics were significantly affected by the interaction treatments. Also, most combined treatments significantly enhanced all examined traits. Moreover, farmyard manure at a high rate (20 m³/fed.) plus inoculation coriander seeds with mixed bacteria and mycorrhizal fungi were the most effective treatments. The main constituents of volatile oil were also affected by farmyard manure and bio-fertilizers applications. In general, the combination of farmyard manure at a high rate (20 m³/fed.) plus inoculation of seeds by mixed bacteria and mycorrhizal fungi increased percentages of main components of volatile oil compared to untreated plants.