Diseased common bean pods, stems, and roots were recognized various fungal pathogens along two growing seasons (2019–2020) in El-Minya governorate, Egypt. Two genera of fungi, Fusarium spp. and Macrophomina phaseolina, were occurred with pods, stems and roots recording the most predominant that showed the highest frequency, in the case of Fusarium 45% and Macrophomina 25%.                                 
   The most infective Fusarium isolate F1 and Macrophomina phaseolina isolate M1 were subjected for molecular identification which confirmed that F1 is Fusarium equiseti and M1 isolate is Macrophomina phaseolina. Soaking seeds in calcium silicate (CaSi) gave significant reduction in disease severity % (DS%) at 0.2g/l by 40.54%, and 33.3% under soil infestation with F. equiseti and M. phaseolina respectively. However, CaSi was more effective to protect common bean plants against either Fusarium equiseti or M. phaseolina infection, than potassium silicate (Psi). Potassium bicarbonate (PB) at 0.2g/l expressed the highest protection values 47.3% and 54.31% against F. equiseti and M. phaseolina infection, respectively. Application of (PAA) at 0.2g/l AA+2.0g/l H₂O₂ as seed soaking resulted in resistant bean plant against F. equiseti 20% protection and against M. phaseolina 47.0% protection. Salicylic acid (SA) caused significant bean DS reduction. Using 0.2g/l SA exhibited 35.22% and 32.74% protection against infection by F. equiseti and M. phaseolina, respectively.