This study aimed to investigate the life skills and their relations to multiple intelligences among female students in the College of Science and Humanities in Huraymila, Shaqra University. The descriptive method was employed, along with a questionnaire to measure life skills and the McKenzie scale to measure multiple intelligences among a sample of 172 female students from the College of Science and Humanities in Huraymila. The study revealed several findings, including the following: life skills among female students in the College of Science and Humanities in Huraymila were at a moderate level, with no statistically significant differences found in the average responses of the study sample regarding the level of life skills among female students based on variables such as specialization (scientific - humanitarian) and academic level (beginning levels - advanced levels). Additionally, female students in the College of Science and Humanities in Huraymila possessed all types of intelligences at a high level, with no statistically significant differences found in the level of multiple intelligences among college students attributed to specialization and academic level variables. The results confirmed a significant positive relationship between the level of life skills and the level of multiple intelligences among female students in the College of Science and Humanities in Huraymila.