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315652

Antibacterial effect of cinnamon essential oil in combination with traditional antibiotics

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Last updated: 05 Jan 2025

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Abstract

Drug-resistant microorganisms are on the rise, posing a danger to successful bacterial illness treatment and increasing the demand for new antibacterial drugs. Natural products are currently and will continue to be the principal source of antibacterial therapeutic agents. This study's aim was to assess the antibacterial effects of Cinnamon essential oil (EO) alone and in combination with several traditional antibiotics against multi-drug resistant Staphylococcus sp.   The antibacterial efficacy was determined using the disc diffusion method. As a result, cinnamon oil possesses antibacterial properties with MICs were 1.25 mgml-1 and 2.5 mgml-1 for S. epidermidis and S. aureus, respectively. Commercial antimicrobials and essential oil work together most effectively when combined. Scanning electron microscopy revealed morphological alterations in Staphylococcus cells, indicating cell membrane damage. Cinnamon essential oil composition was assessed using GC/MS with polonicumtoxin B (14.71%), linalool (5.36%), cinnamaldehyde (3.37%), 5, 5-dimethyl-4-hydroxy-1-phenyl-1-hexen-3-one (6.47%), 2-methyl benzofuran (5.79%), and 1,2-propanediol (6.32%). This study presented a natural product as a substitute for chemical therapeutics, addressing the problem of antibiotic resistance.

DOI

10.21608/fjard.2023.315652

Keywords

MDR Staphylococcus, cinnamon oil, Antimicrobials, Synergy, GC/MS

Authors

First Name

Amany

Last Name

M. M. Reyad

MiddleName

-

Affiliation

Microbiology, Botany Department, Faculty of Science, Fayoum University

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Orcid

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Volume

37

Article Issue

4

Related Issue

43274

Issue Date

2023-10-01

Receive Date

2023-09-02

Publish Date

2023-10-01

Page Start

673

Page End

686

Print ISSN

1110-7790

Online ISSN

2805-2528

Link

https://fjard.journals.ekb.eg/article_315652.html

Detail API

https://fjard.journals.ekb.eg/service?article_code=315652

Order

315,652

Type

Research articles.

Type Code

1,920

Publication Type

Journal

Publication Title

Fayoum Journal of Agricultural Research and Development

Publication Link

https://fjard.journals.ekb.eg/

MainTitle

Antibacterial effect of cinnamon essential oil in combination with traditional antibiotics

Details

Type

Article

Created At

28 Dec 2024