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313448

Longitudinal Data with Intermittent Missing Values: A Sensitivity Analysis Approach

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Last updated: 28 Dec 2024

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Abstract

Intermittent missing data are not uncommon in longitudinal data studies. In selection models, the probability of being missing for any observation is modeled as a function of the current observation and the previous observations. The parameter that relates the probability of missingness and the current observation has special interpretation. The degree of informativeness of the missing data process depends on this parameter's value. We conduct sensitivity analysis to evaluate the effect of this parameter value (the sensitivity parameter) on study results. In the proposed approach, the sensitivity parameter is assumed to be fixed at a set of plausible values. This allows us to examine several degrees of informativeness of the missing data process. The stochastic EM algorithm is used to obtain parameter estimates. The proposed method is evaluated via a simulation study and then applied to a real data set. Sensitivity analysis shows that the conclusion depends on the degree of informativeness. Hence, when estimating the sensitivity parameter the results should be interpreted cautiously.

DOI

10.21608/esju.2007.313448

Keywords

Diggle, Kenward Model, informative missing, Intermittent missing, selection models, the stochastic EM algorithm

Volume

51

Article Issue

2

Related Issue

42973

Issue Date

2007-12-01

Publish Date

2007-12-01

Page Start

37

Page End

47

Print ISSN

0542-1748

Online ISSN

2786-0086

Link

https://esju.journals.ekb.eg/article_313448.html

Detail API

https://esju.journals.ekb.eg/service?article_code=313448

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1

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Original Article

Type Code

1,914

Publication Type

Journal

Publication Title

The Egyptian Statistical Journal

Publication Link

https://esju.journals.ekb.eg/

MainTitle

Longitudinal Data with Intermittent Missing Values: A Sensitivity Analysis Approach

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Type

Article

Created At

28 Dec 2024