This study investigated factors affecting the infection by Fusarium oxysporum and F. proliferatum causing cloves rot (CR) of garlic and developing CR disease during storage. Results showed that the Balady cultivar was the most susceptible to CR disease caused by F. oxysporum and F. proliferatum, which exhibited the lowest cloves germination and disease severity index (DSI) after 21 of planting, followed by Chinese cv. In contrast, Seds 40 cv. was the least susceptible to the CR disease, followed by American cv. During storage of garlic bulbs under room conditions, Balady cv. has exhibited the highest disease progress of CR caused by F. oxysporum and F. proliferatum after 30, 60, and 90 days, followed by Chinese cv. On the other hand, Seds 40 cv. has exhibited the lowest disease progress of CR, followed by American cv. Also, 30 °C was the most affecting the CR disease progress of garlic caused by both fungi and gradually increased the DSI of CR of stored bulbs after 90 of storage, followed by 25 °C. In contrast, 20 °C was the least affecting the progress of CR disease during storage.