To determine the most important stages for skipping (withholding) irrigation, Investigate the role of silicon and irrigation rates in alleviating water stress effect on improving wheat production in the much critical stages, and Investigation the effect of K-silicate as an anti-stress substance on wheat under drought stress has been investigated, a field factorial experiment on wheat was carried out during the 2021–2022 growing season. Six treatments make up the first factor. The following treatments were used: I₀ no skipping; I₁ skipping at tillering (20 days after seeding "AS"); and I₂ skipping at the vegetative stage (45 days AS). I₃ skips flowering (60 days AS), I₄ skips milk (90 days AS), and I₅ skips the dough stage (110 days AS). Two Si treatments were performed: S₁ normal Si and S₂ Nano dose (2, 4, and 6 mLSiL^-1) spray solutions of D₁, D₂, and D₃. Plants treated with K silicate produced yields ranging from 6.116 from S₁D₁I₁ to 8.615 from S₂D₃I₀, representing increases of 3.6 to 45.9%, respectively, over the non-Si treatments' average yield. Plants not getting silicates produced grain yields of I₁ (withholding irrigation during tillering) and I₀ (without withholding), which ranged in size from 5.045 to 6.175 Mgha-1, respectively. Plants that received silicates produced grain yields that ranged from 5.413 from S₁C₁I₁ to 8.279 from S₂C₃I₀, a growth of 52.95%. The main consequence of the Nano application is a rise of 5.04%. I₁ (skipping at tillering) had the lowest yield of all the irrigation methods, producing 5.958 Mgha-1. The greatest was I₀, which produced 7.926 Mgha^-1, an increase of 33.03%, with no irrigation being withheld. Following is a list of the main effects of irrigation I₁ > I₅ > I₆> I₄ > I₃ > I₂. It can be concluded that S₂ Nano dose at 6 mLSiL^-1 might be used as an anti-stress substance otherwise regardless of the critical wheat growth stages without any further effects on the yield. Moreover, tillering is the most critical wheat growth stage, so it is not recommended to withhold irrigation, especially in this stage.