In the last two decades, the consumption of duck meat has increased rapidly, and it is expected that it will continue to grow in the future. In Egypt, ducks are regarded as a secondary meat source. More focus has been directed in recent years on enhancing meat production through duck breeding. In the rural area, ducks were well-known for their flavorful and tasty meat. Additionally, it's highly disease resistance was stated for a long time. Salmonella considered as one of the most important pathogens that incriminated in several economic losses to poultry industry. Recently, the appearance of antimicrobial resistances in Salmonella isolates contributed to the inability to control Salmonella infection in duck farms.  Therefore this review will focus on the Salmonella isolation from ducks in particular, its incidence rate, serotypes, antimicrobial resistance patterns, different alternative therapy to antibiotics. In Egypt, the incidence rates of Salmonella in duck farms ranged from 0.5% to 20%. The most common serotype that recorded in duck farms was S. Typhimurium. The highest antibiotic resistances reported were aganist amoxicillin, cephradine, colistin sulfate, ampicillin, tetracycline, streptomycin, lincomycin and erythromycin. Recently, the misuses of antibiotics results in bacterial resistances in both human and animal fields. Therefore, the need to find alternatives to antibiotics is an important issue. Some substances like lactic acid, Prebiotics, probiotics, symbiotics, essential oils, cinnamaldehyde, organic acids, nanoparticles and chitosan exhibited antibacterial effectively against Salmonella. One of the most effective control measures against Salmonella was bacteriophage treatments that prevent bacterial colonization in the intestinal tracts of birds. The vaccines may provide promising results in the control and prevention of avian Salmonellosis. The findings in this review highlighted the needs of antimicrobial surveillances and biosecurity programs that should be implemented to control the Salmonella infections in different duck farms.