ABSTRACT: This study was conducted in the Biological Control Laboratory, Department of Economic Entomology and Agricultural Zoology, Faculty of Agriculture, Menoufia University, in order to estimate the efficiency of two types of entomopathogenic nematodes against some insects. In addition to study the effect of some macro and micro fertilizer compounds used in the field on nematodes under test. The experiments were conducted with the purpose of studying the sensitivity of both the greater wax worm larvae and the cotton leaf worm and the cut worm in the fourth, fifth and sixth phase to the infection of the nematode Steinernema carpocapsae and Heterorhabditis bacteriophora 24,48 and 72 hours after infection with a concentration of 50, 100, 200, 400. And 800 and 1600 nematodes /10 larvae/dish under laboratory conditions 21 ± 4 ºC and 72 ± 5 relative humidity %.