This study seeks to examine relationship between talent management practices and level of psychological capital revealed in the Egyptian pharmaceutical sector, the researcher throughout this research tries also to test the mediating role that organizational justice might perform in shaping this relationship. Simple random sample from employees & workers working within various managerial levels inside Arab drug & chemicals industries company was selected in order to test research hypotheses. Results revealed positive significant relationship between both talent recruitment dimension and talent management & evaluation dimension and level of organizational justice revealed, also positive significant impact was found between procedural justice dimension & level of psychological capital. However, in presence of organizational justice as a mediating variable, no significant impact was found between both retaining talents dimension & talents development dimension and level of psychological capital. Finally, in absence of organizational justice as a mediating variable, no significant impact was found between recruiting talents dimension & level of psychological capital.