The main objective of this research was to investigate the moderating role of brand reputation in the relationship between perceived risk and customers' behavior in online shopping. The study focused on customers of online stores in Egypt. Employing an analytical descriptive approach, data were gathered from 474 customers through an online questionnaire. Statistical analysis was conducted using SPSS V 22 and AMOS V 22 software, with structural equation modeling utilized for hypothesize testing. Results indicated a significant negative impact of perceived risk dimensions (financial risk and non-delivery risk) on both brand reputation and online shopping behavior. Moreover, brand reputation was found to positively influence online shopping behavior and also served as a moderator between perceived risk dimensions and online shopping behavior. The study further contributed by developing the "Perceived Risk Reduction" (PRR) model as a theoretical implication.