Back ground: Providing the best possible care for children requires the 
introduction of different therapeutic techniques for a wide range of congenital 
heart defects. Aim: To evaluate the effect of mothers' instructional guidelines 
on selected post therapeutic cardiac catheterization outcomes among children. 
Subject and Method: Research Design: Quasi-experimental research design 
was used in the present study. Setting: The study was conducted at Post 
Cardiac Catheterization Intensive Care Unit of Cairo University Specialized 
Pediatric Hospital. Subject: Purposive sample of 60 mothers of children who 
underwent Cardiac Catheterization were included and divided into two equal 
group, study and control groups. Tools of data collection: Structured 
Questionnaire sheet, Assessment of Mother's Knowledge, Assessment of 
Mother's Reported Practises and Post Cardiac Catheterization Assessment 
Record were used. Results: There was a statistically significant difference in 
the total mean vital signs scores immediately after Cardiac Catheterization and 
one week after Cardiac Catheterization for the children in the study group, and 
in the mean knowledge and practice scores of the mothers in both groups. 
Conclusion: A significant increase in knowledge and practice in caring for 
children after Cardiac Catheterization was reported while following 
instructional guidelines. Moreover, children of mothers who received 
educational guidance had fewer problems after Cardiac Catheterization. 
Recommendation: Extensive prospective randomized studies are required to 
enhance postnatal outcomes