Background: Awareness of performance appraisal (PA) justice is pivotal that can influence Intensive Care (IC) nurses' productivity and satisfactions, besides creative self-efficacy. Aim of the study: Explore perception of justice in performance appraisal in relation to IC nurses' creative self-efficacy at Tanta University and El-Menshawy General Hospitals. Methods: Design: A correlational-comparative research design was applied Subjects: A convenience sample of all IC nurses (n=510) were working at Tanta University and El-Menshawy General Hospitals. Tools: Two tools were used: Nurses' Perception of Justice in Performance Appraisal and Nurses' Creative SelfEfficacy Questionnaires. Results: 64.2 % of IC nurses at Tanta University Hospital had moderate perception level of total justice in PA and, 45.7% of El- Menshawy Hospital nurses had low level. 54.3% and 44.2% of IC nurses at Tanta University and El- Menshawy General Hospitals had moderate level of total creative selfefficacy. Conclusion: There was a statistically significant positive correlation between IC nurses' perception of justice in performance appraisal and creative self-efficacy in both hospitals. Recommendation: Equip nursing supervisors with the required knowledge and skills about performance appraisal strategies and technique through training programs.