Background: Humble leaders do inspire the initiatives and efforts of their staff and this has been found to enhance nurses' job crafting and creativity in respect to performance and effectiveness Aim: Determining humble leadership and its relation to staff nurses' job crafting and creativity. Design: Descriptive, correlational research. Setting: Critical care units and in-patient department at the National Liver Institute, Shibin al-Kom, Menoufia Governorate. Study subjects: A convenient sampling technique was used (n=297) who are working at the above-mentioned units and departments. Tools: Three tools of data collection were used: Humble Leaders Questionnaire, Job Crafting Scale, and Creativity Scale. Results: Nursing managers have had a moderate level of humble leadership from staff nurses' perspective. Also, staff nurses had a moderate level job crafting and a high level of creativity. Conclusion: High statistical significance between nursing managers' humble leadership and staff nurses' job crafting and creativity has been found out. Recommendation: Nurse Managers create a work environment that helps nurses craft their jobs in order to enhance job creativity and avoid counterproductive work behavior.