The present study aimed to investigate the impact of using three antibiotics on mulberry silkworm Bombyx mori L. were investigated. Those antibiotics were Ibidroxil (250mg) containing cefadroxil monohydrate, Cefaclor (250mg) containing cefaclor and Rame-dinir (250 mg) active ingredient was cefdinir. Three concentrations of each antibiotic were prepared (10,50 and 100mg).
Mulberry leaves soaked in each concentration and introduced to the 4^th instar larvae and continuos till to matured larvae. Nineteen economic characters were studied. Insignificant differences were recorded in all treatments for all characters under study except FD and TD. Lowest average values were recorded for control followed by blank treatment. Highest averages were registered for ibidroxil followed by cefaclor and Rame-dinir treatments.The best averages were observed for highest concentration 100  mg followed by 50 mg and 10 mg. So that, the application by any concentration for all antibiotic under study was enhanced the economic characters of silkworm, Bombyx mori L.