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280279

Evaluation of Photochemical Components, Antioxidant Properties and Cytotoxicity Effects of Some Egyptian Algae Extracts on Some Cancer Cells

Article

Last updated: 04 Jan 2025

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CHEMISTRY

Abstract

In this work, two marine green macro algae are potential (Enteromorpha intestinalis and Ulva lactuca species) as a source of several critical bioactive substances. Bioactive phenolic and flavonoids compounds were explored. Antioxidant properties and anticancer effects, such as cytotoxicity of different extracts of Enteromorpha sp < /em> and Ulva lactuca sp, have been investigated. The methanolic extracts have the most robust free radical activity (91.89 %) as well as ethyl acetate (86.70%), followed by water extract (82.47 %) and hexane extract (77.25 %) of Ulva sp comparedto ascorbic acid as standard (98.16%). Percentage inhibition on free radical scavenging generation by the methanolic extract was found to be increasing in Enteromorpha sp < /em> (83.85 %), followed by water extract (81.14%); ethyl acetate extract (80.56 %) and hexane extract (71.76%). The methanolic extract of Enteromorpha sp < /em> and Ulva sp < /em> yielded data demonstrating a high total phenolic content of 66.8 and 40.3 as mg GAE /g sample, respectively. The Enteromorpha sp < /em> and Ulva sp < /em> extracted with methanol were significantly higher in their content of total flavonoids (49.4 and 32.1 as quercetin mg/g sample, respectively) than the other extracts. The obtained data reveal that methanol extract had the highest anticancer activity. There was no inhibition of all cancer cells of the samples extracted with water. The results showed that this type of algae contains unique and innovative chemical active antitumor components and can act as an antioxidant and anti-carcinogenic agent of the liver and colon for future applications in the pharmaceutical industries.

DOI

10.21608/assjm.2023.280279

Keywords

Marine algae, Enteromorpha intestinalis, Ulva lactuca species, Antioxidant activity, Anticancer activity

Authors

First Name

Farhat

Last Name

Fouda

MiddleName

-

Affiliation

Biochemistry banha

Email

farhat.fouda@fagr.bu.edu.eg

City

-

Orcid

Frahat F.A. Foda

Volume

61

Article Issue

1

Related Issue

40776

Issue Date

2023-03-01

Receive Date

2023-01-14

Publish Date

2023-03-01

Page Start

77

Page End

86

Print ISSN

1110-0419

Online ISSN

2974-4830

Article File

ASSJM_Volume 61_Issue 1_Pages 77-86.pdf

PDF . 1.2MB

Link

https://assjm.journals.ekb.eg/article_280279.html

Detail API

https://assjm.journals.ekb.eg/service?article_code=280279

Order

4

Type

Original Article

Type Code

841

Publication Type

Journal

Publication Title

Annals of Agricultural Science, Moshtohor

Publication Link

https://assjm.journals.ekb.eg/

MainTitle

Evaluation of Photochemical Components, Antioxidant Properties and Cytotoxicity Effects of Some Egyptian Algae Extracts on Some Cancer Cells

Details

Type

Article

Created At

24 Dec 2024