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349916

Use of Carbopol as an adjuvant in preparation of inactivated rabbit pasteurellosis vaccine

Article

Last updated: 24 Dec 2024

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Subjects

-

Tags

Microbiology

Abstract

The current study was designed to investigate the immunological response of rabbits vaccinated with the rabbit pasteurellosis vaccine adjuvanted with Carbopol®. One hundred and twenty, 2 weeks old rabbits were divided into four groups, 30 for each. The first group was received the formalized P. multocida vaccine. The second group was received the Montanide ISA206 P. multocida vaccine. The third group was received the Carbopol P. multocida vaccine. The fourth group was left unvaccinated as a control group. The prepared vaccines were evaluated by the measurement of the antibody response by the indirect haemagglutination (IHA) and ELISA techniques. The vaccines' potency was assessed using the challenge test against the virulent strains of P. multocida serotypes A and D. The findings revealed that the Carbopol® rabbit pasteurellosis vaccination elicited a strong and long-lasting antibody response, as well as a considerable protection against the virulent strains of P. multocida serotypes A and D.

DOI

10.21608/bvmj.2024.264635.1777

Keywords

Pasteurella, Rabbits, Carbopol, Montanide

Authors

First Name

Fatma

Last Name

Ibrahim

MiddleName

Fathy

Affiliation

Aerobic Bacterial vaccines Research Department, Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Agricultural Research Center (ARC), 131, Cairo, Egypt

Email

dr.fatma_vet@yahoo.com

City

-

Orcid

-

First Name

Manal

Last Name

Mohamed

MiddleName

Fawzy

Affiliation

Aerobic Bacterial vaccines Research Department, Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Agricultural Research Center (ARC), 131, Cairo, Egypt

Email

manalfawzy201@gmail.com

City

Cairo

Orcid

-

First Name

Wafaa

Last Name

Abd El-Moneim

MiddleName

Sayed

Affiliation

Aerobic Bacterial vaccines Research Department, Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Agricultural Research Center (ARC), 131, Cairo, Egypt

Email

wafasaed80@gmail.com

City

Cairo

Orcid

-

First Name

Naglaa

Last Name

Ali

MiddleName

-

Affiliation

Department of pet animal vaccine Research, Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Agricultural Research Center (ARC), 131, Cairo, Egypt

Email

naglaaaly20093@yahoo.com

City

Cairo

Orcid

-

Volume

46

Article Issue

1

Related Issue

47107

Issue Date

2024-04-01

Receive Date

2024-02-12

Publish Date

2024-04-01

Page Start

130

Page End

134

Print ISSN

1110-6581

Online ISSN

2974-4806

Article File

BVMJ_Volume 46_Issue 1_Pages 130-134.pdf

PDF . 366.5kB

Link

https://bvmj.journals.ekb.eg/article_349916.html

Detail API

https://bvmj.journals.ekb.eg/service?article_code=349916

Order

24

Type

Original Article

Type Code

812

Publication Type

Journal

Publication Title

Benha Veterinary Medical Journal

Publication Link

https://bvmj.journals.ekb.eg/

MainTitle

Use of Carbopol as an adjuvant in preparation of inactivated rabbit pasteurellosis vaccine

Details

Type

Article

Created At

24 Dec 2024