Background: The quality of the relationship between nurses and their supervisors affects their embeddedness to the workplace, and eliminate their intention to leave it. Aim: This study aimed at assessing perceived supervisor support and its influence on job embeddedness among staff nurses. Research design: A descriptive, correlational design was used. Setting: The study was conducted at Cairo Fatemic hospital, which affiliated to specialized medical centers. Subjects: The study subjects consisted of 110 staff nurses out of 150 working in afore mentioned setting. Tools: Data were collected by using two tools: perceived supervisor nursing support questionnaire and job embeddedness scale. Results: The majority of studied nurses (81.8%) had high perception level regarding nursing supervisor support, more than three fifth of studied nurses (61.9%) had high level of job embeddedness, while less than one third of studied staff nurses (30%) had moderate level of job embeddedness. Conclusion: There was significant positive correlation between nursing supervisor support and job embeddedness among staff nurses. Recommendations: Conducting a regular meeting among the supervisors and nurses to discuss and solve their work problems, improving work place environment among nurses.