Sixty samples of salted Om El-Kholoul were improvement of the microbial quality of the collected from different localities in Giza, Alexandria and Ismailia. Collected sampels were examined organoleptically and subjected to bacteriological examination for enumeration of Aerobic, enterobacteriaceae, Staph. aureus, enterococci counts as well as isolation and 
identification of Vibrio parahaemolyticus.The mean  counts/gm of Aerobes, Enterobacteriaceae, Staph. aureus, Strept. faecalis and Strept. faecum were 4.9 x 155, 4.8 x 104,1.9x105, 1.5 x 105, and 8 x 102, respectively. V. parahaemolyticus could be isolated from all examined samples. The weight, pH and sodium chloride percent of ten sampels were estimated and the inhibitory Om El-Kholoul (Wedge shell-Donax trunculus) is effect of lemon juice (Citrus aurantifolia) onthe 
microbial load of such samples was noticed. The public health significance of isolated microorganisms and the suggestive measures for improvement of the microbial quality of the product were discussed.