A total of 6000 buffaloes (Bubalus bubalis) slaughtered for meat production at Cairo abattoir were examined at post-mortem during 1991 -1992 for the presence of Cysticercus bovis, sarcosporidia, hydatid cysts, liver flukes and tuberculosis. The incidence rate was 0.32%, 0.88%, 0.60%, 8.44% and 4.96% for affections respectivley. Fascioliasis constituted nearly 80% of the parasitic affections. The lungs showed tuberculous nodules in 70.41% of the cases. Suggestive measures for control of such affections were mentioned.