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377380

TRIALS FOR PREPARATION OF A COMBINED INACTIVATED VACCINE OF SALMONELLOSIS AND FOWEL CHOLERA IN POULTRY

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Immunology / vaccine / diagnosis
Virology and viral diseases

Abstract

In an attempt for preparation a combined inactivated vaccine containing P. multocida, S.typhimurium and S. enteritidis, this vacine was injected in a dose of 0.5ml S/C twice one month apart, in groups of chickens. The humoral immunity was measured by  indirect haemagelutination (IHA) and enzyme linked immunosobent assay (ELISA) test. The combined vaccine elicited high levels of antibody and Showed protection rate of 96.5% against virulent challenge with these bacteria. The cellular immune response was measured by 3-(4,5 - dimethyl- thiazol - 2- yl) 2,5- diphenyl tetrazolium bromide  (MTT) utilization test and heterophil /lymphocyte ratio. the conjugation of these organisms conferred T-dependent properties on their lipopolysaccharides. The combination had no mutual competitive effect but enchancing each other including improvement the immunogenicity of fowl cholera vaccine. The combined vaccine seems to be a good economical value for poultry industry with less shedding of salmonellae after challenge with virulent strain.

DOI

10.21608/vmjg.1998.377380

Authors

First Name

EMAN M.

Last Name

EL-RAWY

MiddleName

-

Affiliation

Veterinary serum and vaccine Research Institute, Abbasia, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

NAHED

Last Name

I.M.M. KHAMIS

MiddleName

-

Affiliation

Veterinary serum and vaccine Research Institute, Abbasia, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

SAMIRA

Last Name

A.A. SOLIMAN

MiddleName

-

Affiliation

Veterinary serum and vaccine Research Institute, Abbasia, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

GRRGIS

Last Name

S.M

MiddleName

-

Affiliation

Veterinary serum and vaccine Research Institute, Abbasia, Cairo, Egypt.

Email

-

City

-

Orcid

-

Volume

46

Article Issue

4

Related Issue

49902

Issue Date

1998-10-01

Receive Date

2024-08-31

Publish Date

1998-10-01

Page Start

867

Page End

875

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 46_Issue 4_Pages 867-875.pdf

PDF . 2.8MB

Link

https://vmjg.journals.ekb.eg/article_377380.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=377380

Order

377,380

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

TRIALS FOR PREPARATION OF A COMBINED INACTIVATED VACCINE OF SALMONELLOSIS AND FOWEL CHOLERA IN POULTRY

Details

Type

Article

Created At

23 Dec 2024