Clinical examination of 1550 adult animals of different breeds (500 cattle, 350 buffaloes, 400 sheep and 300 goats) in Governmental and private populations, showed that a number of 406 amimals were suffering from foot disease problems (128 cattle, 35 buffaloes, 163 sheep and 75 goats) . A total of 198 cases of claw diseases exhibiting different lesions in different animals were microbiologically examined. The incidence of aerobic and facultative anaerobic bacteria isolated from different claw diseases were mainly E.coli (21.71%) , Ps. aeruginosa (25.75%), Pr. mirabilis (24.74%), A. Pyogenes (65.15%), B. anthracoides (46.46%), S. aureus (42,92%), S. epidermidis (21.71%), S.saprophyticus (21.71%) and Strep. faecalis (18,68%). Although, the incidence of obligatory anaerobic bacteria isolated were mainly F. necrophorum (65.65%), Bact. melaninogenicus (50%), Bact. nodosus (9.59%), Anaerobic streptococci (37.87%) adn C. perfringens type A (46.96%), The isolated fungi were mainly Mucor Spp. (40.4%), Candida spp. (16.16%) . Penicillium spp. (6.06%) , Rhizopus spp. (6.56%) and Aspergillus spp. (9.09%). The applied preventive measures, together with specific therapy after antibiotic sensitivity test had successfuly solved these foot problems.