Beta
ManageSearchChatDiscover
377365

FREPARATION OF A SPECIFIC PESTE DESPETTIS RUMINANTS (PPR) VIRUS VACCCINE

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Immunology / vaccine / diagnosis
Virology and viral diseases

Abstract

A specifc Peste des Petits Ruminants (PPR) virus vaccine was prepared by vira passage of the local strain of PPR virus (Egypt - 87), 20 times on Vero cells . The preprepared vaccine was screened for fungi, Mycoplasma , aerobic and anaerobic bacteria. Identity, safety, potency and extraction of such vaccine virus were tested. Balady sheep and Balady goats were inoculated subcutaneously each with the detected protective dose(103 TCID50) of the vaccine virus. The level of PPR neutralizing antibodies was followed up in the sera of vaccinated animals from the first week till the 52nd week (one year) post vaccination. The antibody titers reached their peak (128) in sheep and (256) in goats by the 3rd week post vaccination and remained unchanged up to one year later. The vaccinated animals did not show any thermal elevation in rectal temperature or abnormal clinical signs. It was concluded that the prepared live attenuated cell culture PPR vaccine is a safe and potent specific vaccine and could be used safely to protect sheep and goat industries against PPR disease.

DOI

10.21608/vmjg.1998.377365

Authors

First Name

M.H

Last Name

KHODEIR

MiddleName

-

Affiliation

Vet. Serum and Vaccine Research Institute ,Abbasia ,Cairo ,Egypt

Email

-

City

-

Orcid

-

First Name

M.A.

Last Name

MOUAZ

MiddleName

-

Affiliation

Vet. Serum and Vaccine Research Institute ,Abbasia ,Cairo ,Egypt

Email

-

City

-

Orcid

-

Volume

46

Article Issue

4

Related Issue

49902

Issue Date

1998-10-01

Receive Date

2024-08-31

Publish Date

1998-10-01

Page Start

709

Page End

717

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 46_Issue 4_Pages 709-717.pdf

PDF . 3.3MB

Link

https://vmjg.journals.ekb.eg/article_377365.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=377365

Order

377,365

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

FREPARATION OF A SPECIFIC PESTE DESPETTIS RUMINANTS (PPR) VIRUS VACCCINE

Details

Type

Article

Created At

23 Dec 2024