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372257

SOME TOXICOLOGICAL STUDIES ON CROTON OIL IN WHITE RATS

Article

Last updated: 23 Dec 2024

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Tags

Physiology/endocrinology

Abstract

  Eighty albino rats of both sexs were used in this study and divided into 4 equal gorups. The first 3 groups were injected with croton oil in a dose of 0.50 and 1.00 mg/k gm B.Wt. respectively while the 4th group kep: as control and injected 0.5 ml tween-80 I/p. Results revealed thar R.B.Cs. count, HB®% and PCV were decreased while W.B.Cs count were increased significantly. Differentual leucocylic count Were Significantly decrease in lymphocytes and significantly increease in neutrophils and monocytes while eosinophil was slightly increased but basophils was not affected. Levels of GOT, GPT and AP were significantly increased, while T.P., albumin and globulin were significantly decreased in serum of toxicated rats. Urea and creatinine were decreased but potassium was increased in camparison to control group. Calcium and phosphorous levels were slightly changes in serum of treated rats. Microscopically the liver was congested with mononuclear aggregation and the hepatocyte suffered from dgenerative changes. The kidney showed haemorrahages with haemosidrosis, mononculear cell.

DOI

10.21608/vmjg.1992.372257

Authors

First Name

H

Last Name

BAKRY

MiddleName

-

Affiliation

Fac Vet.Med. , Zagazig Univ. Banha branch

Email

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City

-

Orcid

-

First Name

H

Last Name

El-MANSOURY

MiddleName

-

Affiliation

Fac. Vet. Med. Cairo Univ.

Email

-

City

-

Orcid

-

First Name

A

Last Name

OSMAN

MiddleName

-

Affiliation

Dept. Theriogenology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

R

Last Name

EL-SHAWARBY

MiddleName

-

Affiliation

Fac Vet.Med. , Zagazig Univ. Banha branch

Email

-

City

-

Orcid

-

Volume

40

Article Issue

2

Related Issue

49631

Issue Date

1992-04-01

Receive Date

2024-08-06

Publish Date

1992-04-01

Page Start

135

Page End

143

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 40_Issue 2_Pages 135-143.pdf

PDF . 2.7MB

Link

https://vmjg.journals.ekb.eg/article_372257.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=372257

Order

372,257

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

SOME TOXICOLOGICAL STUDIES ON CROTON OIL IN WHITE RATS

Details

Type

Article

Created At

23 Dec 2024