Beta
ManageSearchChatDiscover
368352

Teratogenic effects of abamectin in rats

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Theriogenology / reproductive technology

Abstract

    The teratogenic effects of abamectin pesticide on pregnant rats were studied following oral administration of 2.85, 1.42 and 0.72 mg/ kg bw (1/10, 1/20 and 1/40 of the oral LD50, respectively) during the organogenesis period. Treatment with abamectin did not influence the reproductive status (number of uterine implants, resorptions, live and dead fetuses per litter) at all dosage levels. However, it caused significant increase in the percentages of morphological, visceral and skeletal malformations in rat fetuses on exposure to the two high doses compared to control. In addition , abamectin induced different pathological alterations in the placentae and fetal organs in a dose-related manner. 

DOI

10.21608/vmjg.2011.368352

Keywords

Abamectin, Teratogenic, fetuses, placenta, malformations, rat

Authors

First Name

zaghloul

Last Name

H

MiddleName

-

Affiliation

Theriogenology, Departments, Faculty of Veterinary Medicine, Minufiya University, El-Sadat city branch, Egypt

Email

-

City

-

Orcid

-

First Name

El-Ballal

Last Name

S

MiddleName

-

Affiliation

Pathology, Departments, Faculty of Veterinary Medicine, Minufiya University, El-Sadat city branch, Egypt

Email

-

City

-

Orcid

-

First Name

Morgan

Last Name

M

MiddleName

-

Affiliation

toxicology and Forensic Medicine Department, Faculty of Veterinary Medicine, Cairo University, Egypt

Email

-

City

-

Orcid

-

First Name

El Bialy

Last Name

E

MiddleName

-

Affiliation

Forensic Medicine and Toxicology, Departments, Faculty of Veterinary Medicine, Minufiya University, El-Sadat city branch, Egypt

Email

-

City

-

Orcid

-

Volume

59

Article Issue

4

Related Issue

49194

Issue Date

2011-10-01

Receive Date

2024-07-21

Publish Date

2011-10-01

Page Start

299

Page End

305

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 59_Issue 4_Pages 299-305.pdf

PDF . 1.0MB

Link

https://vmjg.journals.ekb.eg/article_368352.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=368352

Order

368,352

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

Teratogenic effects of abamectin in rats

Details

Type

Article

Created At

23 Dec 2024