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330656

Therapeutic effects of Curcumin, Saffron, and Moringa against Aluminum Toxicity in Rats

Article

Last updated: 23 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Bioavailability of nutrients and metabolism

Abstract

Natural plants can help treat some diseases and are a great source of vitamins and minerals for the body. Objective: research the use of moringa, saffron, and curcumin to treat animals from aluminum poisoning. Thirty-five male albino rats weighing around 170 ± 10g were divided into 5 groups (7 rats/ each) as follows: The main first group was kept as a negative control and was fed on the basal diet only. The second main group (28 rats) after six weeks of feeding a normal diet supplemented with aluminum chloride (AlCl3), was divided into four subgroups fed AlCl3 and treated plants for a further four weeks. The first was a positive group that consumed a normal diet with AlCl3. A basal diet mixed with AlCl3 + Moringa (100 mg/kg diet) was provided to subgroup 2.  The consumption of a basal diet combined with 15 mg/kg of saffron and AlCl3 supplied subgroup 3. A basal diet mixed with AlCl3 and curcumin (0.5 g/kg diet) was given to subgroup 4. The findings showed that the plant with the greatest potential to reduce aluminum toxicity was saffron, while moringa improved liver and kidney functions and curcumin helped ameliorate the lipid profile. In conclusion, employing these natural plants can reduce the severity of aluminum poisoning.

DOI

10.21608/bnni.2023.330656

Keywords

Aluminum poisoning, Curcumin, Saffron, Moringa

Authors

First Name

Usama

Last Name

Mustafa

MiddleName

E

Affiliation

Department of Home Economics Nutrition and Food Sciences, Faculty of Specific Education - Ain Shams University,

Email

-

City

Cairo

Orcid

-

First Name

Ereny

Last Name

Nagib

MiddleName

W

Affiliation

Department of Home Economics Nutrition and Food Sciences, Faculty of Specific Education - Ain Shams University,

Email

-

City

Cairo

Orcid

-

First Name

Amal

Last Name

Emara

MiddleName

H

Affiliation

Nutritional Chemistry and Metabolism Department, National Nutrition Institute (NNI) –Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Hamdy

Last Name

El-Basel

MiddleName

A

Affiliation

Nutritional Chemistry and Metabolism Department, National Nutrition Institute (NNI) –Cairo, Egypt

Email

h.elbassel17@gmail.com

City

Cairo

Orcid

-

First Name

Basma

Last Name

“Mohamed Khairy"

MiddleName

G

Affiliation

Department of Home Economics Nutrition and Food Sciences, Faculty of Specific Education - Ain Shams University

Email

-

City

Cairo

Orcid

-

Volume

62

Article Issue

2

Related Issue

42671

Issue Date

2023-12-01

Receive Date

2023-12-17

Publish Date

2023-12-01

Page Start

142

Page End

163

Print ISSN

1110-0974

Online ISSN

2537-0987

Article File

BNNI_Volume 62_Issue 2_Pages 142-163.pdf

PDF . 1.5MB

Link

https://bnni.journals.ekb.eg/article_330656.html

Detail API

https://bnni.journals.ekb.eg/service?article_code=330656

Order

330,656

Type

Original Article

Type Code

442

Publication Type

Journal

Publication Title

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt

Publication Link

https://bnni.journals.ekb.eg/

MainTitle

Therapeutic effects of Curcumin, Saffron, and Moringa against Aluminum Toxicity in Rats

Details

Type

Article

Created At

23 Dec 2024