Turkey meat has a high nutritional value due to its abundance of vitamins, protein, and other growth-promoting ingredients. In this study, 100 turkey samples were gathered from various supermarkets across the governorate of Menofia, Egypt. Microbiological assessment of thigh and breast samples was done by measuring the aerobic plate count (APC), coliforms, Escherichia coli, Salmonella, and Staphylococcus aureus as well as yeast and mould count. Concerning the turkey meat samples, the mean total aerobic count values were 4.01 ± 0.21 log₁₀ CFU/g in the thigh and 3.19 ± 0.13 log¹⁰ CFU/g in the breast. The thigh and breast had mean values of 3.21 ± 0.16 log¹⁰ CFU/g and 2.02 ± 0.11 log¹⁰ CFU/g, respectively, for total coliforms. The Staphylococcus aureus count was 2.11 ± 0.09 log¹⁰ CFU/g in the thigh and 1.85 ± 0.08 log₁₀ CFU/g in the breast. While mould and yeast counts were 3.27 ± 0.11 log¹⁰ CFU/g in the thigh and 2.55 ± 0.04 log¹⁰ CFU/g in the breast. The incidence of E. coli was 42% in thigh samples and 26% in breast samples. Salmonella incidence represented 18% in thigh samples and 10% in breast samples. While the mould and yeast were 22% in thigh samples and 14% in breast samples. In conclusion, food-borne pathogens were found in most samples. These pathogens were higher in the thigh than those in breast samples. Consequently, strict hygiene measures should be conducted during the slaughtering, handling, and transporting of turkey meat.