The experiment was conducted at the research orchard and the laboratories of Pomology Department, Faculty of Agriculture, Assiut University during 2021 and 2022 seasons. The study included one pomegranate cultivar named Manfalouty to study the effect of conventional and nano selenium (N-Se) and nano zinc (N Zinc) both at 5 and 10 ppm on productivity and fruit quality under Assiut conditions.  
The experiment suggested that N zinc application at 5 and 10 ppm significantly exceeded the rest of treatment concerning leaf area, however, the differences between the two concentrations were significant. N-Se at 10 and 5 ppm recorded the highest yield weight while N-Se at 10 ppm recorded the highest number of fruits/tree.  N Zinc at 10 ppm followed by N-Se at 10 ppm and Se at 10 ppm significantly exceed the other treatments in average fruit weight. Generally, Se (conventional or Nano) recorded the highest value of fruit height and diameter, Aril weight, juice volume, and other fruit quality properties.