Two field experiments were conducted at the Experimental Farm of Vegetable Department, Faculty of Agriculture, Assiut University, Egypt, to observe the effect of harvest time and planting method under two different planting dates on cassava yield and its components (c.v. Indonisi). Planting dates were on the 1^st and 15^th of April in 2021/2022 and 2022/2023 seasons, respectively which were laid in two separate experiments. Each experiment is laid out in a Randomized Complete Block Design (RCBD) using a split-plot arrangement with three replications. Where harvesting times (8, 9 and 10 months from planting) were arranged in the main plots while planting methods (direct and stored stakes for 15 days underground) were localized in the subplots. The acquired results exhibited that all the first and second interactions had significant or highly significant effects on tubers yield /fed in both seasons except the interaction between planting date × planting method in the second season. Hence, the highest average values of tuber yield /fed (8.483 and 7.963 tons in the two respective seasons) were obtained from cassava plants which were planted using direct stakes on April 1 and harvested after 9 months from planting. So, to achieve the highest yield from cassava, it will be recommended to cultivate cassava with direct stakes at the beginning of April and harvest after 9 months under Assiut conditions.