Squash is an important vegetable crop and infested by numerous pests. Both cucurbit fly, Dacus ciliatus (Loew) and western flower thrips, Frankliniella occidentalis (Pergande), were mainly pests in squash. Field experiment was implemented biocontrol tactics for controlling these pests on squash. The present results showed a significant effective between all sequentially spraying of six treatments with the untreated field of squash plant against D. ciliatus and                    F. occidentalis infestations during the two investigated fall seasons, 2021 and 2022. The highest D. ciliatus and F. occidentalis infestations on squash was obtained with the 4^th program contained sequentially spraying of Bacillus megaterium, spinetoram and emamectin benzoate plus yeast and 2% honeybee, azadrachtin + 2% black honey and mineral oil and the untreated filed during two tested fall seasons. Contrariwise, the application of 5^th and 6^th programs that contained sequentially spraying of B. megaterium, spinosad bait hydrolyzed protein + kerosene soil drench, orange oil and azadrachtin + 2% black honey gave the best results in reducing D. ciliatus and F. occidentalis infestations on squash during two fall seasons. Squash production increased in all treatments compared with untreated field, but its highest value was 4475.62 kg/feddan during two seasons. Therefore, we could be concluded that the sequentially spraying of 5^th and 6^th programs gave the higher reduction of two pests on squash. Consequently, this study can used to have sound decisions for these pest managements on cucurbits specially squash in Egypt during fall cultivations.