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391266

Antibacterial activity of ethanolic extracts of Thymus vulgaris and Cinnamomum camphora on human pathogenic bacteria.

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Last updated: 05 Jan 2025

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Abstract

Medicinal Various chemical compounds produced by herbs have primary medicinal uses, particularly in treating bacterial diseases, such as nosocomial infections. Thymus Vulgaris Cinnamomum camphora ethanolic extracts were investigated for their antibacterial activity against three hazardous bacteria: Staphylococcus aureus, Acinetobacter baumannii complex, and Klebsiella pneumoniae. The three dangerous bacteria—Staphylococcus aureus, Acinetobacter baumannii complex, and Klebsiella pneumoniae—were detected utilizing the 16rRNA gene extracted from clinical specimens (pneumonia, sputum, urine). Two Egyptian plant extracts, ethanolic (Thymus vulgaris) and the other Cinnamomum camphora, were tested in vitro for antibacterial activity. The Thymus Vulgaris extract showed main inhibition diameters of 27, 30.3, and 20.6 mm against three human pathogenic bacteria, while the Cinnamomum camphora extract showed main inhibition diameters of 25, 27.6, and 18.3 mm.  The gas chromatography-mass spectrometry (GC-MS) examination of the Thymus Vulgaris Cinnamomum camphora extracts indicated the presence of several terpene compounds. The main ingredient (in this order: cis-vaccenic acid, otadecanoic acid, cis-13-eicosenoic acid, erucic acid, oleic acid, 13-docosenoic acid, isochlapin B, thymol, epiplobol).

DOI

10.21608/jbes.2024.391266

Keywords

Acinetobacter baumannii complex, Staphylococcus aureus, Cinnamomum camphora, Klebsiella pneumoniae, Thymus vulgaris

Authors

First Name

Yasmin M.

Last Name

Elsayed

MiddleName

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Affiliation

Botany, Dept., Faculty of Science, Benha Univ., Benha, Egypt

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Orcid

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First Name

Mervat G.

Last Name

Hassan

MiddleName

-

Affiliation

Botany, Dept., Faculty of Science, Benha Univ., Benha, Egypt

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Orcid

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First Name

Amr A.

Last Name

El-Waseif

MiddleName

-

Affiliation

Botany Microbiology Dept., Faculty of Science(Boys), Al-Azhar University,Cairo, Egypt

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Orcid

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First Name

Hamed M.

Last Name

El-Shora

MiddleName

-

Affiliation

Botany Department, Faculty of Science, Mansoura University, Mansoura, Dakahlia, Egypt.

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Orcid

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First Name

Mohamed O.

Last Name

Abdel-Monem

MiddleName

-

Affiliation

Botany, Dept., Faculty of Science, Benha Univ., Benha, Egypt

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Volume

11

Article Issue

4

Related Issue

51467

Issue Date

2024-10-01

Receive Date

2024-11-10

Publish Date

2024-10-01

Page Start

437

Page End

452

Print ISSN

2536-9202

Online ISSN

2356-6388

Link

https://jbes.journals.ekb.eg/article_391266.html

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https://jbes.journals.ekb.eg/service?article_code=391266

Order

391,266

Type

Original Article

Type Code

3,063

Publication Type

Journal

Publication Title

Journal of Basic and Environmental Sciences

Publication Link

https://jbes.journals.ekb.eg/

MainTitle

Antibacterial activity of ethanolic extracts of Thymus vulgaris and Cinnamomum camphora on human pathogenic bacteria.

Details

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Article

Created At

21 Dec 2024