As the demands for healthcare access continue to rise, the depleted Syrian health system is unable to provide an adequate response. The political and economic crises in Syria have cast a vast shadow, that affects the healthcare system and the medical education sector, particularly the postgraduate residency program, where first-year residents are expected to work early to meet the mounting healthcare needs. These residents are working under suboptimal conditions in which both medical and human resources are not appropriately available. In this article, we will address and present the challenges that medical residents face under the pressures of the significant resource limitations.